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Mass Spectrometry for Drug Discovery and Drug Development

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ÁöÀºÀÌ :  Korfmacher
¹ßÇàÀÏ :  2013 ³â
ISBN :  9780470942383
Á¤Çà°¡ :  59,000 ¿ø
ÆäÀÌÁö :  476 ÆäÀÌÁö
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ÃâÆÇ»ç :  Wiley

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1. Overview of the Various Types of Mass Spectrometers that are Used in Drug Discovery and Drug Development

2. Utility of High-Resolution Mass Spectrometry for New Drug Discovery Applications

3. Quantitative Mass Spectrometry Considerations in a Regulated Environment

4. Mass Spectrometry for Quantitative In Vitro ADME Assays

5. Metabolite Identifi cation Using Mass Spectrometry in Drug Development

6. MS Analysis of Biological Drugs, Proteins, and Peptides

7. Characterization of Impurities and Degradation Products in Small Molecule Pharmaceuticals and Biologics

8. Liquid Extraction Surface Analysis (LESA): A New Mass Spectrometry-Based Technique for Ambient Surface Profiling

9. MS Applications in Support of Medicinal Chemistry Sciences

10. Imaging Mass Spectrometry of Proteins and Peptides

11. Imaging Mass Spectrometry for Drugs and Metabolites

12. Screening Reactive Metabolites: Role of Liquid Chromatography–High-Resolution Mass Spectrometry in Combination with ¡°Intelligent¡± Data Mining Tools

13. Mass Spectrometry of siRNA

14. Mass Spectrometry for Metabolomics

15. Quantitative Analysis of Peptides with Mass Spectrometry: Selected Reaction Monitoring or High-Resolution Full Scan?